With High Sensitivity & Lot-To-Lot Consistency
Immunoglobulins are secreted by B-cells and are comprised of heavy (G, A, D, E, or M) and light chains (Kappa and Lambda). Each mature B lymphocyte expresses surface immunoglobulins exclusively bearing only one class of light chains, either Kappa or Lambda with cellular proportions of roughly 2/3 in healthy individuals.
A skewing of this ratio may indicate an expansion of either kappa+ or lambda+ B cell clone. Kappa and Lambda light chains are produced exclusively by B lymphocytes but can also be found at the surface of a variety of non-B cells expressing Fc gamma receptors such as CD64, CD32, CD16.
Features of new anti-Kappa and anti-Lambda antibodies:
- Polyclonal antibodies – higher affinity and sensitivity
- Fragments only – minimized non-specific staining
- ASR Regulatory Status – validated for clinical use in the United States
- Manufactured under cGMP regulations – state of the art and reproducible manufacturing conditions
Disclaimer: Data generated in research context during product development
| Name | Clone | Status | Part No |
|---|---|---|---|
|
Kappa-FITC |
Goat polyclonal |
ASR | C15623 |
|
Lambda-PE |
Goat polyclonal |
ASR | C15189 |
|
Lambda-PC7 |
Goat polyclonal |
ASR |
B90416 |
|
Kappa-APC |
Goat polyclonal |
ASR |
Coming soon |
ASR: Analyte Specific Reagents. Analytical and performance characteristics are not established